NAD+ Complete
NAD+ Complete
- POWERFUL 4-IN-1 Formula - LIPO NAD⁺ Complete combines NAD⁺, NMN, NR and Trigonelline all in one capsule, targeting all pathways to effectively increase NAD⁺ levels throughout the body.*
- SUPPORTS CELLULAR HEALTH - By boosting NAD⁺ levels, LIPO NAD⁺ Complete supports cellular health, energy production, and overall well-being, helping you maintain optimal vitality.*
- TARGETED DELIVERY - Our proprietary, powder-based liposomes protect NAD⁺, NMN, NR and Trigonelline from digestive enzymes and carry them into the bloodstream for targeted systemic delivery, ensuring maximum efficacy.*
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What is NAD+ Complete?
What is NAD+ Complete?
NAD+ is a compound that's vital to life as we know it, used by every living cell in hundreds of biochemical functions. Stress and wear-and-tear on your body over time can deplete your NAD+ supply, and ultimately affect your overall health and well-being.
Some people swear by one NAD+ booster. Some companies want you to believe one is best. NAD+ Complete eliminates having to choose, with a 4-in-1 formula incorporating four studied NAD+ boosters—NMN, NR, trigonelline, and NAD+ itself—into one liposomal formula that helps protect the active ingredients through digestion to provide a more sustained release over time.
Use it consistently on its own to fuel cellular energy production, repair and recovery processes, and the resilience to help you stand up to the stressors of modern life. Or take it alongside your go-to NAD+ booster for added coverage and timed release.
Ingredients & Supplement Facts
Ingredients & Supplement Facts
Active Ingredients:
- NMN (nicotinamide mononucleotide): 310mg
- NAD+ (nicotinamide adenine dinucleotide): 160mg
- NR (nicotinamide riboside): 100mg
- Trigonelline: 70mg
Inactive Ingredients:
- Vegetable Cellulose (capsule)
- Sunflower Lecithin
- Rice Flour
- Microcrystalline Cellulose
Batch Numbers & Certificates of Analysis (COAs)
Batch Numbers & Certificates of Analysis (COAs)
Every batch of supplements we make is independently tested in U.S. laboratories for purity, potency, and quality.
- 072827561 - Potency, Heavy Metals, Microbiology (09/04/2026)
- 072827561 - Potency (08/12/2026)
- RN26042 - Potency (03/19/2026)
- 26042 - Microbiology (02/16/2026)
- 26042 - Heavy Metals (02/16/2026)
- 204001 - Potency (04/25/2025)
Is NAD+ Complete the Right Formula for You?
One Formula, Four Ways to Boost NAD+
Each NAD+ booster supports your NAD+ supply in different ways for full-spectrum energy support.
Cellular Energy
Cellular Energy
NAD+ is used by every living cell to turn the food you eat into usable energy. Increasing your NAD+ supply supports the processes behind generating sustained energy to power your days.†
Repair and Recovery
Repair and Recovery
Your cells are constantly repairing and replacing what everyday stressors can deplete. NAD+ is vital to the processes of repair and recovery.
Healthy Aging
Healthy Aging
NAD+ is involved in hundreds of biochemical functions, from metabolism to maintaining cellular health. Increased NAD+ levels can support the systems that keep you resilient over time.†
NMN
310 MG
CELLULAR ENERGY HEALTHY AGING PHYSICAL PERFORMANCE
A direct precursor to NAD⁺ and the most widely studied NAD⁺ booster, including human research on physical performance in older adults. Found in small amounts in foods like broccoli and avocado, NMN is one enzymatic step away from NAD⁺.†
NAD⁺
160 MG
CELLULAR ENERGY HEALTHY AGING NO CONVERSION REQUIRED
The NAD⁺ coenzyme itself, not a precursor to it. Included so the formula supplies NAD⁺ directly alongside ingredients your body can use to create it.†
NR
100 MG
CELLULAR ENERGY HEALTHY AGING METABOLIC SUPPORT
A direct precursor to NAD⁺ backed by a substantial body of human research, including work on cardiovascular and metabolic health. NR converts to NMN first, then to NAD⁺, so it goes through two steps in the enzymatic conversion process.†
Trigonelline
70 MG
CELLULAR ENERGY HEALTHY AGING MUSCLE HEALTH
A compound found in coffee and fenugreek, identified in recent research as an NAD⁺ precursor linked to muscle health and mitochondrial function.†
Science & QualityYou Can Feel Good About
Every formula is built on established and emerging research and manufactured under pharmaceutical-grade standards, so healthy aging doesn’t require a leap of faith.
Ingredient Purity
Our R&D team works hard to source the highest-quality, purest ingredients. Our products are non-GMO and we strive to keep them free of additives and fillers.
Liposomal Delivery
Our liposomal technology encapsulates fragile active ingredients in protective phospholipids, helping protect them through digestion so more of what you take can be effectively absorbed and utilized by the body.
Third-Party Tested in Certified Labs
Our products are tested in ISO- and cGMP-certified labs to ensure quality, purity, and potency. Certificates of Analysis (COAs) for the exact product you purchased are published on our website; simply use the batch number located on the bottom of your product to match it to your COA.
Made in the USA
All products are manufactured in the United States. We’re committed to ensuring the highest-quality production standards, and our manufacturers maintain strict quality controls throughout the production process, from raw material sourcing to final bottling.
Measured Success at Renue By Science
At Renue By Science, we blend rigorous scientific research with premium-quality ingredients to create supplements that support cellular health, energy, recovery, and healthy aging. Every formula is developed with a clear focus on quality, transparency, and real results.
NAD⁺ Levels May Drop Due to Aging, Health Status & Lifestyle Choices
Your cells rely on a molecule known as NAD⁺. Higher NAD⁺ levels support healthier cellular function. When NAD⁺ declines, you may experience reduced energy, slower recovery and weaker resilience.
Our supplements work through multiple biological pathways to raise, preserve and optimize NAD⁺, supporting its regeneration across tissues in your body — helping you live better, longer.
BOOST
Your body makes NAD+ from precursors like NMN, NR, and Trigonelline. Production naturally slows with age. This pathway replenishes the raw materials your cells need to keep making healthy NAD+ levels.
PROTECT
Producing more NAD+ only helps if your body isn't burning through it just as fast. Enzymes like CD38 ramp up with age, consuming NAD+ before your cells can use it. This pathway helps maintain the levels you're working to build.
OPTIMIZE
NAD+ fuels your mitochondria, but efficiency matters as much as supply. This pathway supports sirtuin activity and mitochondrial function so your cells get more from the NAD+ they have.
REGENERATE
Cellular damage accumulates during the day and creates constant demand on your NAD+ supply. This pathway supports the restorative processes, especially during sleep, that clear that burden.
RENUE BY SCIENCE PROMISE.
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RESEARCH-BACKED
Each ingredient is selected referencing published clinical studies on aging, cellular health and NAD⁺ metabolism. Our formulas follow scientific evidence instead of market trends, and we refine formulations whenever new research emerges.
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CLEAN & SAFE
Vegan, gluten-free and non-GMO. No fillers, artificial additives or redundant ingredients in any formula. Every product is crafted to meet consistent safety standards for your peace of mind. -
THIRD-PARTY TESTED
Every batch undergoes independent testing for identity, purity and potency at ISO & cGMP-certified labs. Test results are publicly available, so you can verify the contents inside each bottle before purchase. -
MADE IN THE USA
Produced in US facilities that meet or exceed current Good Manufacturing Practice standards. Ingredients are third-party tested and sourced from reliable global suppliers.
“At the age of 63, I feel like I have the same strength and endurance from my 30s.“
Bryan Nettles, Founder and CEO of Renue By Science, has a lifelong focus on nutrition, exercise, and longevity science. His personal health journey - recovering from prostate cancer - deepened his commitment to research and healthy aging. Driven to educate and empower others, he founded the company to make science-backed longevity solutions more accessible, helping people live longer, stronger lives at any stage.
Bryan Nettles
Founder & CEO
Dr. Rebecca Crews holds a PhD in Biochemical and Molecular Nutrition from the Friedman School at Tufts University. Her research has spanned the Air Force Research Laboratory, Tufts, and Texas State, with published work on NMN supplementation, metabolic variability, and the science of NAD+ in healthy aging. At Renue By Science, she leads the research program and translates the latest longevity science into the formulas you find in our shop.
Dr. Rebecca Crews
Research Director
Dr. Clark Driggers is the Chief Medical Advisor at Renue By Science, with a clinical focus on wellness, healthy aging, and regenerative medicine. He works at the intersection of clinical practice and longevity research, helping shape the science behind our formulas. His perspective grounds our work in what actually matters to patients in the real world: products that are safe, effective, and built on evidence.
Dr. Clark Driggers
Chief Medical Advisor
Liposomal Delivery Boosts Bioavailability
Liposomal technology encapsulates delicate active compounds such as NMN and NR within phospholipids — the natural fats that form your cell membranes. This protective layer shields ingredients throughout digestion and first-pass liver metabolism.
The outcome: A higher amount of active ingredients reaches your cells. This means lower doses can offer far greater support compared to conventional supplement formulas.
Your longevity, explained.
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How to Pick the Right NMN Formula for You
ENERGY | FOCUS | RECOVERY | CONFIDENCE
Unsure which option fits?
This guide helps you find an NMN formula matching your wellness goals, daily routine and lifestyle. -
Get the Most from NAD⁺ Support Supplements
ENERGY | VITALITY | RESILIENCE | LONGEVITY
New to NAD⁺?
Begin here. Learn the fundamentals: what NAD⁺ is, why it matters, and how to maintain healthy levels as you age. -
Mitochondrial Health: Support Graceful Aging
ENERGY | STRENGTH | STAMINA | HEALTHY AGING
Mitochondria power your cells. Discover how to keep them robust, energized and functioning optimally.
Liposomal Capsules, Designed for Fast Absorption with Targeted Delivery
Our proprietary powder-based liposomes protect NAD⁺, NMN, NR, and Trigonelline from digestive enzymes, helping them enter the bloodstream more efficiently for targeted cellular support. This delivery approach is formulated to maximize absorption and support overall efficacy.
FAQ
Why four NAD+ boosters instead of one?
Why four NAD+ boosters instead of one?
There’s no consensus that one is best. NMN, NR, and trigonelline are precursors your body converts to NAD+, and NAD+ itself is included directly. Rather than betting on one, this formula covers all four.
How is this different from taking NMN or NR on its own?
How is this different from taking NMN or NR on its own?
Single-ingredient products give you one booster and let you control that dose precisely. NAD+ Complete gives you broader coverage in one capsule. Many users take both.
Isn’t NAD+ too large a molecule to absorb?
Isn’t NAD+ too large a molecule to absorb?
It’s a fair question, and it’s why most products use precursors instead. Our liposomal encapsulation is designed to protect NAD+ through digestion. The formula also includes three precursors, so you’re not depending on NAD+ absorption alone.
Do I need to take TMG with this?
Do I need to take TMG with this?
Processing NAD+ precursors draws on your body’s supply of methyl groups, which are also used in other biochemical functions. TMG (trimethylglycine) is a source of methyl groups, and some people take it alongside an NAD+ routine for that reason. Worth discussing with your healthcare provider.
When should I take NAD+ Complete?
When should I take NAD+ Complete?
Most people take it in the morning as part of a consistent routine, but you can take it at whatever time of day works best for you, as long as you take it consistently.
Can I take NAD+ Complete with my other Renue by Science supplements?
Can I take NAD+ Complete with my other Renue by Science supplements?
Yes. NAD+ Complete sits in the Boost pathway and is built to work alongside Protect, Optimize, and Regenerate formulas, and can be taken with other Renue Boost formulas, too.